Table 2 Quantitative FACS analysis of MRP3 expression by biopsies, cell lines, and established xenografts with MAb 16A11
From: MRP3: a molecular target for human glioblastoma multiforme immunotherapy.
Diagnosis | Positive cases/Total cases | Percent | Estimated number of MRP3 molecules per cell |
|---|---|---|---|
Cell Lines | |||
   GBM adult | 6/7 | 86 | 0.1-4.9 × 105 (med. = 1.9 × 105) |
   MED pediatric | 5/5 | 100 | 0.7--2 × 105 (med. = 1 × 105) |
Biopsies | |||
   AA adult | 3/6 | 50 | 1.7--2.7 × 104 |
   GBM adult | 22/27 | 82 | 0.17--6.5 × 105 (med. = 6.5 × 104) |
Xenografts | |||
   GBM adult | 4/7 | 57 | 0.2--2.1 × 105 |
   MED pediatric | 2/3 | 67 | 1.6--2.5 × 104 |