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Table 2 Quantitative FACS analysis of MRP3 expression by biopsies, cell lines, and established xenografts with MAb 16A11

From: MRP3: a molecular target for human glioblastoma multiforme immunotherapy.

Diagnosis Positive cases/Total cases Percent Estimated number of MRP3 molecules per cell
Cell Lines
   GBM adult 6/7 86 0.1-4.9 × 105 (med. = 1.9 × 105)
   MED pediatric 5/5 100 0.7--2 × 105 (med. = 1 × 105)
Biopsies
   AA adult 3/6 50 1.7--2.7 × 104
   GBM adult 22/27 82 0.17--6.5 × 105 (med. = 6.5 × 104)
Xenografts
   GBM adult 4/7 57 0.2--2.1 × 105
   MED pediatric 2/3 67 1.6--2.5 × 104