Comparing the frequency of common genetic variants and haplotypes between carriers and non-carriers of BRCA1 and BRCA2deleterious mutations in Australian women diagnosed with breast cancer before 40 years of age

Table 7 Comparison of individual BRCA2 haplotype frequencies

Haplotype	Deleterious mutation noncarriers (standard error)	Deleterious mutation carriers (standard error)	All (standard error)	Chi square (Permutation)	P value (Permutation)
AGAT	0.691 (0.017)	0.527 (0.018)	0.685 (0.017)	0.953	0.329
AGAC	0.043 (0.002)	0.000 (0.000)	0.041 (0.007)	0.046	0.830
AGGT	0.004 (0.002)	0.036 (0.007)	0.005 (0.003)	2.062	0.151
AGGC	0.148 (0.003)	0.258 (0.016)	0.152 (0.013)	0.513	0.474
AAAT	0.023 (0.005)	0.008 (0.003)	0.022 (0.005)	0.000	1.000
AAGC	0.037 (0.007)	0.063 (0.009)	0.038 (0.007)	0.002	0.965
GGAT	0.054 (0.008)	0.107 (0.011)	0.056 (0.008)	0.132	0.716
Overall				3.708	0.717

ISSN: 1471-2407