Skip to main content

Table 2 Comparison between IHC or FISH results and histopathological parameters

From: Molecular alterations in key-regulator genes among patients with T4 breast carcinoma

Characteristics FISH analysis IHC analysis
  CyclinD1 h-prune p53 pERK1-2 survivin
  positive cases % positive cases % positive cases % positive cases % positive cases %
Total patients (N = 53) 12 23 8 15 13 25 5 9 21 40
Estrogen receptor (ER)           
   negative (N = 20) 2 10 1 5 4 20 2 10 9 45
   positive (N = 24) 7 29 5 11 5 21 2 8 7 29
Progesterone receptor (PR)           
   negative (N = 28) 5 18 2 7 5 18 2 7 13 46
   positive (N = 16) 4 25 4 25 4 25 2 12 3 19
Ki67           
   negative (N = 26) 4 15 3 12 4 15 4 15 11 42
   positive (N = 16) 4 25 2 12 5 31 0 0 5 31
HER2           
   0-1 (N = 16) 5 31 3 19 2 12 2 12 9 56
   2-3 (N = 37) 7 19 5 14 11 30 3 8 12 32