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Table 4 Association of IL-10 polymorphisms with PCa aggressiveness

From: Association of genetic polymorphisms in the interleukin-10 promoter with risk of prostate cancer in Chinese

Allele/Haplotype Early stage (72) Advanced stage (180) P OR (95%CI)
-1082A/G     
A 124(86.1) 338(93.9)   1.00
G 20(13.9) 22(6.1) 0.005* 2.48(1.31~4.70)
-819 C/T     
T 86(59.7) 249(69.2)   1.00
C 58(40.3) 111(30.8) 0.043* 1.51(1.01~2.26)
-592 C/A     
A 86(59.7) 249(69.2)   1.00
C 58(40.3) 111(30.8) 0.043* 1.51(1.01~2.26)
Haplotype     
ATA 82(56.9) 245(68.1)   1.00
ACC 42(29.2) 93(25.8) 0.184 1.35(0.87~2.10)
GTA 4(2.8) 4(1.1) 0.128 2.99(0.73~12.2)
GCC 16(11.1) 18(5.0) 0.008* 2.66(1.30~5.45)
  1. *P < 0.05.