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Table 4 Differentially expressed genes

From: Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models

Entrez ID

Probe name

Gene name

Encoded protein

Log2-fold difference

Adjusted p-value (false discovery rate)

5321

A_23_P11685

PLA2G4A

Phospholipase A2, group IV A

6.4

4.4E-16

55349

A_23_P69293

CHDH

Choline dehydrogenase

3.3

4.0E-13

1757

A_24_P35400

SARDH

Sarcosine dehydrogenase

2.5

7.6E-12

9468

A_24_P941353

PCYT1B

Phosphate cytidylyltransferase 1, choline, beta

1.7

3.7E-9

31896

A_23_P87401

GDPD5

Glycerophosphodiester phosphodiesterase domain containing 5

1.0

4.2E-6

8681

A_23_P403424

PLA2G4B

Phospholipase A2, group IV B

0.9

9.8E-5

9791

A_23_P168868

PTDSS1

Phosphatidylserine synthase I

0.9

9.6E-7

10434

A_23_P19192

LYPLA1

Lysophospholipase 1

0.9

0.001

3931

A_23_P218237

LCAT

Lecithin-cholesterol acyltransferase

0.8

0.0002

151056

A_23_P56356

PLB1

Phospholipase B1

0.7

0.0001

5337

A_23_P155335

PLD1

Phospholipase D1

0.7

0.0005

  1. Genes directly involved in choline metabolism with significantly higher expression in basal-like (MAS98.12) than luminal-like (MAS98.06) tumors