Figure 4
From: Survivin gene silencing sensitizes prostate cancer cells to selenium growth inhibition
Growth inhibition by survivin knockdown and MSA treatment. PC-3M, C4-2B, and 22Rv1 cells were transfected with the shRNAs and treated with various concentrations of MSA for 66 hr. Cell numbers were quantitated by the MTT assay. The viability of the mock-transfected control cells were set arbitrarily to 100% and the viabilities of other samples were expressed as percentage of the control. The data presented are mean ± SD (n = 18). Control, mock-tranfected cells. Sh-scrambled, cells transfected with sh-scrambled. Sh-survivin, cells transfected with sh-survivin. *, P < 0.01 vs MSA alone; #, P < 0.01 vs sh-survivin alone.