Experimental setting (A) and reduction in salivary flow rates on day 3 following radiation (B). The head and neck region of FVB mice was exposed to a single dose of 5 Gy radiation. Stimulated salivary flow rates were determined as described in the materials and methods section on day 3 with 81 animals in the untreated (UT) and 72 animals in the treated group. Significant differences (p < 0.05) were determined using an ANOVA followed by a Bonferroni test. (*) in figure 1B over 5Gy treatment group indicates significant differences between groups.