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Table 1 Overview of patient age, gender and mutations found in MSI-H CRCs

From: Mutations in the WTX- gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers

Patient ID Age Gender WTX APC
Exon 15
AXIN2
Exon 8
CTNNB1
Exon 3
KRAS
Codon 12/13
BRAF
Codon 600
1 65 m T5 WT WT WT WT WT
2 n.a. f T5 WT WT WT WT c.1799T>A
3 52 m T6 WT WT WT WT WT
4 74 m T6 WT 1 bp del (G)
codon 665
WT WT n.a.
5 68 f T6 WT WT WT c.35G>A WT
6 28 m T6 2 bp del (AG)
codon 1462
WT WT WT WT
7 72 f T6 WT WT WT WT c.1799T>A
8 65 f T6 n.a. n.a. n.a. WT WT
9 63 f T6 c.2312A>G
p.E770G
WT WT WT c.1799T>A
10 n.a. m T6 c.2393A>G
p.G797D
WT WT WT c.1799T>A
11 77 f T6 WT WT WT WT WT
12 65 f T6 WT WT WT WT c.1799T>A
13 75 m T6 1 bp ins (A)
codon 1554
WT WT WT c.1799T>A
14 69 f T6 WT c.2062C>T (mut/mut)
p.P687L
c.64G>A
p.V22I
WT WT
15 72 f T6 WT WT WT WT c.1799T>A
16 46 m T6 WT c.2073C>T
p.691Q>STOP
WT WT WT
17 45 f T6 1 bp ins (A)
codon 1554
WT WT WT c.1799T>A
18 42 m T6 WT WT WT WT WT
19 n.a. m T6 WT WT WT WT WT
20 76 m T6 WT WT WT WT c.1799T>A
21 76 m T6 WT WT WT WT WT
22 78 f T6 WT c.2037C>T
p.H679Y and
c.2071C>T
p.691Q>STOP
WT WT WT
23 56 f T6 WT WT c.134C>T
p.S45F
WT c.1799T>A
24 33 m T6 WT WT WT WT WT
25 73 f T6 WT WT WT WT c.1799T>A
26 65 f T6 WT c.2103T>C
p.S701P
WT WT c.1799T>A
27 77 f T6 WT WT WT WT WT
28 69 m T6 WT WT WT WT WT
29 43 m T6 WT WT WT WT WT
30 64 f T6 WT WT WT WT WT
31 43 m T6 WT WT WT WT WT
32 43 m T6 WT WT WT WT WT
33 54 m T6 WT WT WT WT WT
34 66 f T6 WT c.2062C>T
p.P687L
WT WT WT
35 40 f T6 WT WT WT WT WT
36 60 m T6 n.a. n.a. n.a. n.a. WT
37 63 f T6 WT WT WT c.35G>A WT
38 73 m T6 WT WT WT WT WT
39 72 f T6 WT c.2077A>G
p.H692R
WT WT WT
40 65 f T6 n.a. n.a. n.a. WT n.a.
41 52 m T6 c.2626C>T
p.876R>STOP
and
2 bp del (AG)
codon 1462
WT WT WT WT