Table 1 Overview of patient age, gender and mutations found in MSI-H CRCs
Patient ID | Age | Gender | WTX | APC Exon 15 | AXIN2 Exon 8 | CTNNB1 Exon 3 | KRAS Codon 12/13 | BRAF Codon 600 |
|---|---|---|---|---|---|---|---|---|
1 | 65 | m | T5 | WT | WT | WT | WT | WT |
2 | n.a. | f | T5 | WT | WT | WT | WT | c.1799T>A |
3 | 52 | m | T6 | WT | WT | WT | WT | WT |
4 | 74 | m | T6 | WT | 1 bp del (G) codon 665 | WT | WT | n.a. |
5 | 68 | f | T6 | WT | WT | WT | c.35G>A | WT |
6 | 28 | m | T6 | 2 bp del (AG) codon 1462 | WT | WT | WT | WT |
7 | 72 | f | T6 | WT | WT | WT | WT | c.1799T>A |
8 | 65 | f | T6 | n.a. | n.a. | n.a. | WT | WT |
9 | 63 | f | T6 | c.2312A>G p.E770G | WT | WT | WT | c.1799T>A |
10 | n.a. | m | T6 | c.2393A>G p.G797D | WT | WT | WT | c.1799T>A |
11 | 77 | f | T6 | WT | WT | WT | WT | WT |
12 | 65 | f | T6 | WT | WT | WT | WT | c.1799T>A |
13 | 75 | m | T6 | 1 bp ins (A) codon 1554 | WT | WT | WT | c.1799T>A |
14 | 69 | f | T6 | WT | c.2062C>T (mut/mut) p.P687L | c.64G>A p.V22I | WT | WT |
15 | 72 | f | T6 | WT | WT | WT | WT | c.1799T>A |
16 | 46 | m | T6 | WT | c.2073C>T p.691Q>STOP | WT | WT | WT |
17 | 45 | f | T6 | 1 bp ins (A) codon 1554 | WT | WT | WT | c.1799T>A |
18 | 42 | m | T6 | WT | WT | WT | WT | WT |
19 | n.a. | m | T6 | WT | WT | WT | WT | WT |
20 | 76 | m | T6 | WT | WT | WT | WT | c.1799T>A |
21 | 76 | m | T6 | WT | WT | WT | WT | WT |
22 | 78 | f | T6 | WT | c.2037C>T p.H679Y and c.2071C>T p.691Q>STOP | WT | WT | WT |
23 | 56 | f | T6 | WT | WT | c.134C>T p.S45F | WT | c.1799T>A |
24 | 33 | m | T6 | WT | WT | WT | WT | WT |
25 | 73 | f | T6 | WT | WT | WT | WT | c.1799T>A |
26 | 65 | f | T6 | WT | c.2103T>C p.S701P | WT | WT | c.1799T>A |
27 | 77 | f | T6 | WT | WT | WT | WT | WT |
28 | 69 | m | T6 | WT | WT | WT | WT | WT |
29 | 43 | m | T6 | WT | WT | WT | WT | WT |
30 | 64 | f | T6 | WT | WT | WT | WT | WT |
31 | 43 | m | T6 | WT | WT | WT | WT | WT |
32 | 43 | m | T6 | WT | WT | WT | WT | WT |
33 | 54 | m | T6 | WT | WT | WT | WT | WT |
34 | 66 | f | T6 | WT | c.2062C>T p.P687L | WT | WT | WT |
35 | 40 | f | T6 | WT | WT | WT | WT | WT |
36 | 60 | m | T6 | n.a. | n.a. | n.a. | n.a. | WT |
37 | 63 | f | T6 | WT | WT | WT | c.35G>A | WT |
38 | 73 | m | T6 | WT | WT | WT | WT | WT |
39 | 72 | f | T6 | WT | c.2077A>G p.H692R | WT | WT | WT |
40 | 65 | f | T6 | n.a. | n.a. | n.a. | WT | n.a. |
41 | 52 | m | T6 | c.2626C>T p.876R>STOP and 2 bp del (AG) codon 1462 | WT | WT | WT | WT |