Table 3 Methylation levels of 7 genes in primary breast cancer tissues and lymph nodes metastasis

HIN-1

6.5 ± 3.2

36.4 ± 26.5

33.1 ± 24.2

0.624

< 0.001

CDH13

3.0 ± 1.2

20.0 ± 17.9

20.6 ± 17.5

0.545

< 0.001

RIL

9.1 ± 3.4

34.5 ± 24.6

36.8 ± 26.2

0.547

< 0.001

RASSF1A

4.0 ± 4.7

28.0 ± 19.8

28.3 ± 21.3

0.233

0.16

RARβ2

1.1 ± 1.2

16.4 ± 21.6

12.3 ± 18.5

0.472

0.003

E-cadherin

4.0 ± 2.5

7.8 ± 8.8

7.8 ± 9.1

0.093

0.583

LINE-1

66.8 ± 3.4

58.3 ± 9.8

58.3 ± 10.9

0.614

< 0.001