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Table 1 Relationship between EGFR mutation, EGFR copy number and clinicopathological characteristics of lung adenocarcinoma

From: Relationship between EGFR expression, copy number and mutation in lung adenocarcinomas

 

IHC

 

Mutation

 

FISH

 
 

+

-

P value

+

-

P value

+

-

P value

Gender

         

   Male

41

21

0.595

34

28

0.042

27

35

0.753

   Female

50

21

 

51

20

 

29

42

 

Age

         

   >60

50

23

0.984

51

22

0.115

30

43

0.795

   <60

41

19

 

34

26

 

26

34

 

Smoking status

         

   Positive

61

25

0.400

62

24

0.008

36

20

0.938

   Negative

30

17

 

23

24

 

50

27

 

Lymph node metastasis

         

   Positive

59

28

0.836

58

29

0.363

33

54

0.180

   Negative

32

14

 

27

19

 

23

23

 

Stage

         

   I

47

22

0.937

45

24

0.744

22

47

0.021

   II

15

2

 

12

5

 

11

6

 

   III

21

12

 

19

14

 

14

19

 

   IV

8

6

 

9

5

 

8

6

 
  1. After Bonferroni correction, P < 0.01 was considered as significant, only the association between EGFR mutation and smoking status was statistically significant.
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BMC Cancer

ISSN: 1471-2407

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