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Table 2 The genotype and allele frequency of MMP-3 in OSMF, HNSCC patients and controls.

From: Synergistic effect of stromelysin-1 (matrix metalloproteinase-3) promoter (-1171 5A->6A) polymorphism in oral submucous fibrosis and head and neck lesions

Groups Total
(N)
5A/5A
Genotype
5A/6A
Genotype
6A/6A
Genotype
5A allele frequency OR 95%CI P-value
Control 126 2 (1.58%) 14 (11.1%) 110 (87.3%) 0.07 1 - -
OSMF 101 3(2.9%) 24 (23.7%) 74 (73.3%) 0.15 2.26 1.22-4.20 0.01
HNSCC 135 6 (4.44%) 23 (17.03%) 106 (78.52%) 0.13 1.94 1.06-3.51 0.03
  1. [OR = Odd Ratio; CI = confidence interval; MMP = matrix metalloproteinase; OSMF = oral submucous fibrosis; HNSCC = Head and neck squamous cell carcinoma]