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Table 2 The genotype and allele frequency of MMP-3 in OSMF, HNSCC patients and controls.

From: Synergistic effect of stromelysin-1 (matrix metalloproteinase-3) promoter (-1171 5A->6A) polymorphism in oral submucous fibrosis and head and neck lesions

Groups

Total

(N)

5A/5A

Genotype

5A/6A

Genotype

6A/6A

Genotype

5A allele frequency

OR

95%CI

P-value

Control

126

2 (1.58%)

14 (11.1%)

110 (87.3%)

0.07

1

-

-

OSMF

101

3(2.9%)

24 (23.7%)

74 (73.3%)

0.15

2.26

1.22-4.20

0.01

HNSCC

135

6 (4.44%)

23 (17.03%)

106 (78.52%)

0.13

1.94

1.06-3.51

0.03

  1. [OR = Odd Ratio; CI = confidence interval; MMP = matrix metalloproteinase; OSMF = oral submucous fibrosis; HNSCC = Head and neck squamous cell carcinoma]