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Table 5 Association of clinical and genotypic parameters with progression free survival (PFS) according to surgery status.

From: A polymorphism at the 3'-UTR region of the aromatase gene defines a subgroup of postmenopausal breast cancer patients with poor response to neoadjuvant letrozole

  No surgery Surgery
Parameters n Events %PFS p n Events %PFS p
Ki67         
   Negative 17 5 66.9 0.686 23 1 50.0 0.023
   Positive 5 1 80.0   27 8 69.6  
RR4M         
   Responders 10 0 100 0.041 25 1 95.2 0.030
   Non-responders 20 6 58.8   40 11 47.8  
rs4646         
   CC 13 0 100 0.009 44 7 81.5 0.790
   AC/AA 17 6 44.1   21 5 59.0