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Table 5 Association of clinical and genotypic parameters with progression free survival (PFS) according to surgery status.

From: A polymorphism at the 3'-UTR region of the aromatase gene defines a subgroup of postmenopausal breast cancer patients with poor response to neoadjuvant letrozole

 

No surgery

Surgery

Parameters

n

Events

%PFS

p

n

Events

%PFS

p

Ki67

        

   Negative

17

5

66.9

0.686

23

1

50.0

0.023

   Positive

5

1

80.0

 

27

8

69.6

 

RR4M

        

   Responders

10

0

100

0.041

25

1

95.2

0.030

   Non-responders

20

6

58.8

 

40

11

47.8

 

rs4646

        

   CC

13

0

100

0.009

44

7

81.5

0.790

   AC/AA

17

6

44.1

 

21

5

59.0

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