Table 4 Risk Factors Associated with OS in 83 Chinese Patients with PGL
| Univariate Analysis | Multivariate Analysis | |||
|---|---|---|---|---|
| Variable |
Mean survival of OS (months) (95%CI) | P value |
RR (95%CI) | P value |
| Sex | ||||
| Female | 67 (55,80) | 0.622 | ||
| Male | 52 (43,62) | |||
| Age | ||||
| ≤ 60 years | 66 (55,76) | 0.795 | ||
| > 60 years | 44 (34,53) | |||
| B symptoms | ||||
| No | 67 (55,79) | 0.186 | ||
| Yes | 60 (49,71) | |||
| LDH | ||||
| ≤ 245 U/L | 81 (70,91) | < 0.0001 | Not significant | |
| > 245 U/L | 45 (33,56) | |||
| Extranodal involvement (excluding stomach) | ||||
| No | 67 (58,76) | 0.112 | ||
| Yes | 37 (15,58) | |||
| Lugano staging | ||||
| I-II1 | 88 (78,97) | < 0.0001 | Not significant | |
| ≥ II2 | 49 (39,59) | |||
| ECOG performance status (PS) | ||||
| 0-1 | 71 (62,80) | < 0.0001 |
8.08 (3.13, 20.89) | 0.0001 |
| ≥ 2 | 17 (5,29) | |||
| Histological subtypes1 | ||||
| DLBCL | 65 (54, 76) | 0.098 | ||
| MALT | 78 (61, 95) | |||
| T-cell lymphomas | 37 (17, 59) | |||
| mIPI | ||||
| 0-1 | 87 (78,95) | < 0.0001 |
8.49 (2.50, 28.85) | 0.001 |
| ≥ 2 | 44 (33,54) | |||
| Bulky disease | ||||
| No | 73 (63,83) | 0.004 | Not significant | |
| Yes | 42 (28,57) | |||
| Leucocytopenia | ||||
| No | 65 (56,75) | 0.955 | ||
| Yes | 39 (23,56) | |||
| Neutropenia | ||||
| No | 65 (55,74) | 0.833 | ||
| Yes | 40 (24,56) | |||
| Lymphocytopenia | ||||
| No | 68 (59,78) | 0.023 | Not significant | |
| Yes | 42 (20,63) | |||
| Anemia | ||||
| No | 72 (58,82) | 0.235 | ||
| Yes | 60 (47,72) | |||
| Albumin | ||||
| ≥ 35 g/L | 73 (64,83) | 0.003 | Not significant | |
| < 35 g/L | 44 (29,58) | |||