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Table 2 Selected top enriched GO terms

From: Characterization of the apoptotic response of human leukemia cells to organosulfur compounds

ID Term F H K L N O P Q Lova Taxol
GO:0003723 RNA Binding 0.0 1.2 3.0 0.3 1.9 0.4 0.1 7.2 0.2 0.0
GO:0006412 Translation 0.0 1.2 4.4 1.1 5.1 0.4 0.7 5.8 1.2 0.0
GO:0045765 Regulation of angiogenesis 0.0 0.0 1.1 1.1 1.1 3.7 0.2 1.4 0.3 0.0
GO:0030162 Regulation of proteolysis 0.0 0.0 1.2 0.4 0.3 0.0 0.0 0.7 3.6 0.0
GO:0043122 Regulation of I-kappaB kinase NF-kappaB cascade 0.0 0.0 0.6 3.3 0.4 0.0 0.4 0.0 1.3 0.0
GO:0046870 Cadmium ion binding 0.0 0.0 0.0 0.5 1.3 3.1 0.0 0.8 0.0 2.3
GO:0006935 Chemotaxis 1.8 0.5 2.0 0.4 1.5 0.9 1.5 0.7 2.9 1.3
  1. Genes that were differentially expressed (padjusted < 0.05) by each compound were subjected to Gene Ontology enrichment analysis using the GOMiner tool with 1,000 permutations. The -log10|P| for selected GO terms are shown here. For example, genes annotated as being involved in RNA binding are enriched amongst those differentially expressed by compound Q with p < 10-7.2 and amongst those differentially expressed by compound H with p < 10-1.2.