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Table 5 Survival and p-values with focus on subgroups of GIST regarding Cyclin H expression

From: Cyclin H expression is increased in GIST with very-highrisk of malignancy

High-Risk DSS DFS
Cyclin H positive
(n = 11)
negative
(n = 28)
all
(n = 39)
positive
(n = 11)
negative
(n = 28)
all
(n = 39)
1-year probability (%) 75 93 89 51 53 52
3-year probability (%) 50 77 71 26 49 44
5-year probability (%) 33 73 65 26 41 38
   Log-Rank Test (p) p = 0.038   p = 0.522  
Tumour Recurrence or Metastases DSS DFS
Cyclin H positive
(n = 7)
negative
(n = 20)
all
(n = 27)
positive
(n = 7)
negative
(n = 20)
all
(n = 27)
1-year probability (%) 67 90 84.9 27 30 30
3-year probability (%) 33 64 57.0 0 25 19
5-year probability (%) 0 58 47.5 0 10 7
   Log-Rank Test (p) p = 0.016   p = 0.362  
  1. (results of immunostaining)