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Table 5 Survival and p-values with focus on subgroups of GIST regarding Cyclin H expression

From: Cyclin H expression is increased in GIST with very-highrisk of malignancy

High-Risk

DSS

DFS

Cyclin H

positive

(n = 11)

negative

(n = 28)

all

(n = 39)

positive

(n = 11)

negative

(n = 28)

all

(n = 39)

1-year probability (%)

75

93

89

51

53

52

3-year probability (%)

50

77

71

26

49

44

5-year probability (%)

33

73

65

26

41

38

   Log-Rank Test (p)

p = 0.038

 

p = 0.522

 

Tumour Recurrence or Metastases

DSS

DFS

Cyclin H

positive

(n = 7)

negative

(n = 20)

all

(n = 27)

positive

(n = 7)

negative

(n = 20)

all

(n = 27)

1-year probability (%)

67

90

84.9

27

30

30

3-year probability (%)

33

64

57.0

0

25

19

5-year probability (%)

0

58

47.5

0

10

7

   Log-Rank Test (p)

p = 0.016

 

p = 0.362

 
  1. (results of immunostaining)