Variable | Single-variate analyses | Multivariate analysis | ||||
---|---|---|---|---|---|---|
 | Crude HR | 95% CI | P value | AHR | 95% CI | P value |
25OHD, ng/mL | 0.99 | 0.94-1.05 | 0.75 | 0.98 | 0.89-1.08 | 0.67 |
Age at surgery, years | 0.98 | 0.96-1.01 | 0.26 | 1.02 | 0.96-1.08 | 0.57 |
Gender, female | 1.36 | 0.65-2.85 | 0.41 | 1.14 | 0.24-5.34 | 0.87 |
Time period of surgery | Â | Â | Â | Â | Â | Â |
May 2003 - December 2005 | 1.45 | 0.67-3.13 | 0.87 | 1.32 | 0.28-6.19 | 0.73 |
January 2006 - January 2008 | reference | Â | Â | Â | Â | Â |
Stage | Â | Â | Â | Â | Â | Â |
Stage I | 0.00 | - | - | 0.00 | - | - |
Stage II | 0.00 | - | < 0.001 | 0.00 | - | - |
Stage III | 0.01 | 0.04-0.20 | < 0.001 | 0.49 | 0.02-10.28 | 0.65 |
Stage IV | Reference | Â | Â | Reference | Â | Â |
Location of tumor | Â | Â | Â | Â | Â | Â |
Proximal colon | 0.77 | 0.31-1.88 | 0.56 | 0.66 | 0.17-2.56 | 0.54 |
Distal colon | 0.56 | 0.18-1.74 | 0.32 | 0.36 | 0.05-2.44 | 0.30 |
Rectum | Reference | Â | Â | Reference | Â | Â |
Type of resection, % | Â | Â | Â | Â | Â | Â |
R0 | 0.03 | 0.01-0.07 | < 0.001 | 0.02 | 0.00-0.75 | 0.034 |
R1 | 0.94 | 0.40-2.18 | 0.88 | 0.51 | 0.07-3.52 | 0.49 |
R2 | Reference | Â | Â | Reference | Â | Â |
Adjuvant chemotherapy | 6.24 | 1.89-20.62 | 0.003 | 0.65 | 0.09-4.85 | 0.67 |
Number of lymph nodes with metastasis*2 | 1.08 | 1.05-1.12 | < 0.001 | 1.13 | 1.04-1.23 | 0.003 |