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Figure 2 | BMC Cancer

Figure 2

From: Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice

Figure 2

Reduced density of blood vessels in tumors recovered from HB-19 treated RET mice. Sections of tumors from control untreated (panel A; localized under the ear) and HB-19 treated (panel B; localized under the eye) RET mice were stained with antibodies against the CD34 endothelial marker and analyzed by fluorescence microscopy (Methods). Representative macroscopic images (magnification 200×) from each group of sections are presented. C. Quantification of angiogenesis was estimated by image analysis of CD34-labeled endothelial cells in tumor sections from control and HB-19 treated RET mice. Statistical significance: * 0.01 < p < 0.1.

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BMC Cancer

ISSN: 1471-2407

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