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Table 5 Correlation of tumor grade versus SMAD4 gene status versus KRAS gene status

From: SMAD4 - Molecular gladiator of the TGF-β signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRASproto-oncogene

 

Mutants

  
 

KRAS N = 21

SMAD4 N = 16

χ2, P value

Both N = 11

Tumor Grade

    

A + B = 38

6 (28.6%)

2 (12.5%)

 

2 (18.2%)

C + D = 48

15 (71.4%)

14 (87.5%)

6.63, 0.03

9 (81.8%)

    

OR = 0.28; 95% CI = 0.05-1.37

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BMC Cancer

ISSN: 1471-2407

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