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Table 4 Cox regression analysis of independent factors affecting disease-free survival, cancer-specific survival and overall survival

From: Different significance between intratumoral and peritumoral lymphatic vessel density in gastric cancer: a retrospective study of 123 cases

Factors Cancer-Specific Survival Disease-Free Survival Overall Survival
  OR (95% CI) P OR (95% CI) P OR (95% CI) P
P-LVD 2.099(0.91-4.87) 0.084 2.418(1.08-5.40) 0.031 2.895 (1.02-8.19) 0.045
I-LVD 1.205(0.56-2.63) 0.639 1.325(0.62-2.85) 0.472 1.959 (0.90-4.24) 0.088
VEGF-A 1.386(0.50-3.83) 0.528 1.364(0.67-2.78) 0.391 2.437(1.10-5.45) 0.030
VEGF-C 2.423(0.89-6.63) 0.085 1.630(0.77-3.47) 0.205 1.562 (0.79-3.34) 0.182
VEGF-D 0.511(0.19-1.36) 0.178 1.916(0.90-4.10) 0.094 1.621 (0.81-3.98) 0.190
LVI 2.716 (1.05-7.04) 0.040 2.477(1.03-5.97) 0.043 2.578 (1.05-6.34) 0.039
LNM 2.115(0.68-6.60) 0.197 2.428(1.18-5.02) 0.017 3.426 (1.66-7.06) 0.001
VI 2.943(0.89-9.77) 0.078 1.697(0.75-3.87) 0.208 1.477(0.63-3.48) 0.373
P-VEGFR-3 1. 499(0.98-2.31) 0.067 1.099(0.53-2.28) 0.800 1.402 (0.68-2.90) 0.361
TNM stage 1.523(1.00-2.31) 0.048 1.674(1.25-2.25) 0.001 1.656(1.23-2.23) 0.001
  1. Abbreviation: P-LVD: peritumoral lymphatic vessel density; I-LVD: intratumoral lymphatic vessel density; LVI: lymphatic vessel invasion; LNM: lymph node metastasis; VI: venous invasion; P-VEGFR-3: VEGFR-3 positive expression at the tumor periphery.