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Table 4 Cox regression analysis of independent factors affecting disease-free survival, cancer-specific survival and overall survival

From: Different significance between intratumoral and peritumoral lymphatic vessel density in gastric cancer: a retrospective study of 123 cases

Factors

Cancer-Specific Survival

Disease-Free Survival

Overall Survival

 

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

P-LVD

2.099(0.91-4.87)

0.084

2.418(1.08-5.40)

0.031

2.895 (1.02-8.19)

0.045

I-LVD

1.205(0.56-2.63)

0.639

1.325(0.62-2.85)

0.472

1.959 (0.90-4.24)

0.088

VEGF-A

1.386(0.50-3.83)

0.528

1.364(0.67-2.78)

0.391

2.437(1.10-5.45)

0.030

VEGF-C

2.423(0.89-6.63)

0.085

1.630(0.77-3.47)

0.205

1.562 (0.79-3.34)

0.182

VEGF-D

0.511(0.19-1.36)

0.178

1.916(0.90-4.10)

0.094

1.621 (0.81-3.98)

0.190

LVI

2.716 (1.05-7.04)

0.040

2.477(1.03-5.97)

0.043

2.578 (1.05-6.34)

0.039

LNM

2.115(0.68-6.60)

0.197

2.428(1.18-5.02)

0.017

3.426 (1.66-7.06)

0.001

VI

2.943(0.89-9.77)

0.078

1.697(0.75-3.87)

0.208

1.477(0.63-3.48)

0.373

P-VEGFR-3

1. 499(0.98-2.31)

0.067

1.099(0.53-2.28)

0.800

1.402 (0.68-2.90)

0.361

TNM stage

1.523(1.00-2.31)

0.048

1.674(1.25-2.25)

0.001

1.656(1.23-2.23)

0.001

  1. Abbreviation: P-LVD: peritumoral lymphatic vessel density; I-LVD: intratumoral lymphatic vessel density; LVI: lymphatic vessel invasion; LNM: lymph node metastasis; VI: venous invasion; P-VEGFR-3: VEGFR-3 positive expression at the tumor periphery.