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Table 2 Correlations of VEGFR-3 expression at differenr tumor location with clinical parameters

From: Different significance between intratumoral and peritumoral lymphatic vessel density in gastric cancer: a retrospective study of 123 cases

Factors N I-VEGFR-3 P-VEGFR-3
   N (%) P N (%) P
VEGF-A expression    0.107   0.067
   Low 44 16(36.36)   15(34.09)  
   High 79 18(22.78)   40(50.63)  
VEGF-C expression    0.795   < 0.001
   Low 42 11(26.19)   9 (21.43)  
   High 81 23(28.40)   46(56.79)  
VEGF-D expression    0.968   0.043
   Low 72 20(27.78)   27(37.50)  
   High 51 14(27.45)   28(54.90)  
P-LVD    0.813   <0.001
   <14 60 16(26.67)   10(16.67)  
   ≥ 14 63 18(28.57)   45(71.43)  
I-LVD    0.412   0.153
   <8 58 14(24.14)   22(37.93)  
   ≥ 8 65 20(30.77)   33(50.77)  
Lymph node metastasis    0.934   0.190
   Negative 55 19(34.55)   21(38.18)  
   Positive 68 15(22.06)   34(50.00)  
LVI    0.681   0.003
   Negative 76 22(28.95)   26(34.21)  
   Positive 47 12(25.53)   29(61.70)  
VI    0.387   0.448
   Negative 87 26(29.89)   37(42.53)  
   Positive 36 8 (22.22)   18(50.00)  
  1. Abbreviation: LVD: lymphatic vessel density; LVI: lymphatic vessel invasion; VI: venous invasion; I-VEGFR-3: VEGFR-3 positive expression in the tumor center; P-VEGFR-3: VEGFR-3 positive expression at the tumor periphery.