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Table 1 2 × 2 contingency table used for testing the significance of gene/protein enrichment in all IKB pathway annotations.

From: Inferring predominant pathways in cellular models of breast cancer using limited sample proteomic profiling

 

Focus Genes

Non-focus Genes

Row Total

Genes associated with pathway

k

n - k

n

Genes not associated with pathway

K - k

(N - n) - (K - k)

N - n

Column Total

K

N - K

N