Table 5 The association between family history of previous cancer and risk of lung cancer in a population based case-control study, Greater Toronto Area, Ontario, 1997-2002
| Â | Total Population n = 1393 | Â | Never smokers n = 622 | Â | ||||
|---|---|---|---|---|---|---|---|---|
| Â | Case, n | Control, n | ORa | 95%CI | Case, n | Control, n | ORb | 95%CI |
| Â | 445 | 948 | Â | Â | 156 | 466 | Â | Â |
No family history of any cancer | 246 | 563 | 1.0 | Refc | 95 | 293 | 1.0 | Refd |
Positive family history of any cancer | Â | Â | Â | Â | Â | Â | Â | Â |
   1 | 141 | 292 | 1.1 | 0.8-1.4 | 42 | 134 | 0.9 | 0.6-1.4 |
   2 or more | 58 | 93 | 1.3 | 0.9-1.9 | 19 | 39 | 1.4 | 0.8-2.8 |
   Affected relatives age at onset < 50 | 82 | 126 | 1.3 | 0.9-1.9 | 28 | 48 | 1.8 | 1.0-3.2 |
Positive family history of aero-digestive cancer | 45 | 78 | 1.2 | 0.8-1.8 | 11 | 34 | 0.9 | 0.4-1.9 |
Positive family history of lung cancer | 30 | 63 | 1.0 | 0.6-1.7 | 8 | 26 | 0.9 | 0.4-2.1 |