Genotypes | Patients (n = 409) | Controls (n = 301) | Crude OR (95% CI) | P-valuea | Adjusted OR (95% CI)b | P-value |
---|---|---|---|---|---|---|
 | n (%) | n (%) |  |  |  |  |
IL-8 (-251)T/A | Â | Â | Â | Â | Â | Â |
TT | 84 (20.5) | 92 (30.6) | 1 | Â | 1 | Â |
TA | 201 (49.2) | 138 (45.8) | 1.60 [1.09-2.34] | 0.01 | 1.71 [1.13-2.55] | 0.009 |
AA | 124 (30.3) | 71 (23.6) | 1.91 [1.24-2.96] | 0.002 | 2.03 [1.56-3.67] | 0.001 |
Alleles | Â | Â | Â | Â | Â | Â |
T-allele | 369 (45.1) | 322 (53.5) | Â | Â | Â | Â |
A-allele | 449 (54.9) | 280 (46.5) | 1.40 [1.13-1.74] | 0.001 | 1.86 [1.79-2.45] | 0.001 |
CXCR2 (+1208)C/T | Â | Â | Â | Â | Â | Â |
CC | 195 (46.7) | 155 (51.5) | 1 | Â | 1 | Â |
CT | 167 (40.8) | 128 (42.5) | 1.04 [0.75-1.43] | 0.81 | 1.31 [0.90-1.69] | 0.63 |
TT | 47 (11.5) | 18 (6.0) | 2.08 [1.12-3.88] | 0.01 | 2.89 [1.48-4.55] | 0.008 |
Alleles | Â | Â | Â | Â | Â | Â |
C-allele | 557 (6.81) | 438 (7.28) | Â | Â | Â | Â |
T-allele | 261 (31.9) | 164 (27.2) | 1.25 [0.99-1.59] | 0.05 | 1.37 [1.09-1.88] | 0.03 |