Figure 2
From: hTERT promoter activity and CpG methylation in HPV-induced carcinogenesis
hTERT promoter activity analysis, using hTERT reporter constructs carrying different promoter and proximal exonic sequences. (A) Schematic representation of different reporter constructs used. (B) Luciferase activity in Saos-2, EK04-3, FK16A, FK16B, FK18A, FK18B, SiHa, HeLa and CaSki cells following transfection of hTERT-1821/-23 and hTERT-499/-23, relative to hTERT-297/-23 that was set at 100%. (C) Luciferase activity in Saos-2, EK04-3, FK16A, FK16B, FK18A, FK18B, SiHa, HeLa and CaSki following transfection of hTERT-297/+81 and hTERT-297/+357, relative to hTERT-297/-23 that was set at 100%.