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Table 2 Predictive value of abnormal mRNA levels for identifying high-grade glioma

From: Differential expression of centrosomal proteins at different stages of human glioma

   Group  
mRNA Low-grade glioma (n= 11) High-grade glioma (n= 23) p-value
hNinein isoform 1 >Normal 2 (18.2%) 9 (39.1%) 0.274
  Normal 9 (81.8%) 14 (60.9%)  
hNinein isoform 2 >Normal 2 (18.2%) 5 (21.7%) 1.000
  Normal 9 (81.8%) 18 (78.3%)  
hNinein isoform 5 >Normal 2 (18.2%) 8 (34.8%) 0.438
  Normal 9 (81.8%) 15 (65.2%)  
hNinein isoform 6 <Normal 3 (27.3%) 14 (60.9%) *
  Normal 8 (72.7%) 9 (39.1%)  
γ-tubulin >Normal 2 (18.2%) 18 (78.3%) 0.002
  Normal 9 (81.8%) 5 (21.7%)  
Aurora A >Normal 0 (0%) 3 (13.0%) 0.535
  Normal 11 (100.0%) 20 (87.0%)  
Aurora B >Normal 2 (18.2%) 3 (13.0%) 1.000
  Normal 9 (81.8%) 20 (87.0%)  
Centrin 2 >Normal 7 (63.6%) 16 (69.6%) 1.000
  Normal 4 (36.4%) 7 (30.4%)  
Centrin 3 >Normal 7 (63.6%) 19 (82.6%) 0.388
  Normal 4 (36.4%) 4 (17.4%)  
  1. NOTE: "Normal" is equivalent to the level of mRNA expression observed in the normal brain tissue.
  2. * No p-value could be calculated because neither group showed a moderate or abundant increase in mRNA expression (see Table 1).
  3. P < 0.05 by Fisher's exact test