Table 2 Predictive value of abnormal mRNA levels for identifying high-grade glioma
From: Differential expression of centrosomal proteins at different stages of human glioma
Group | ||||||
|---|---|---|---|---|---|---|
mRNA | Low-grade glioma (n= 11) | High-grade glioma (n= 23) | p-value | |||
hNinein isoform 1 | >Normal | 2 | (18.2%) | 9 | (39.1%) | 0.274 |
Normal | 9 | (81.8%) | 14 | (60.9%) | ||
hNinein isoform 2 | >Normal | 2 | (18.2%) | 5 | (21.7%) | 1.000 |
Normal | 9 | (81.8%) | 18 | (78.3%) | ||
hNinein isoform 5 | >Normal | 2 | (18.2%) | 8 | (34.8%) | 0.438 |
Normal | 9 | (81.8%) | 15 | (65.2%) | ||
hNinein isoform 6 | <Normal | 3 | (27.3%) | 14 | (60.9%) | * |
Normal | 8 | (72.7%) | 9 | (39.1%) | ||
γ-tubulin | >Normal | 2 | (18.2%) | 18 | (78.3%) | 0.002† |
Normal | 9 | (81.8%) | 5 | (21.7%) | ||
Aurora A | >Normal | 0 | (0%) | 3 | (13.0%) | 0.535 |
Normal | 11 | (100.0%) | 20 | (87.0%) | ||
Aurora B | >Normal | 2 | (18.2%) | 3 | (13.0%) | 1.000 |
Normal | 9 | (81.8%) | 20 | (87.0%) | ||
Centrin 2 | >Normal | 7 | (63.6%) | 16 | (69.6%) | 1.000 |
Normal | 4 | (36.4%) | 7 | (30.4%) | ||
Centrin 3 | >Normal | 7 | (63.6%) | 19 | (82.6%) | 0.388 |
Normal | 4 | (36.4%) | 4 | (17.4%) | ||