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Table 2 Distribution of HPV types in ICC specimens from Italy

From: Human Papilloma Virus prevalence and type-specific relative contribution in invasive cervical cancer specimens from Italy

 

HPV type-specific positive cases (n)

HPV prevalence (95% CI) (*)

Relative HPV type contribution (95% CI) (**)

Single types

111

82.2 (75.4-88.8)

91.7 (85.3-96.0)

   HPV16

71

53.0 (44.2-61.7)

58.7 (49.4-67.5)

   HPV18

12

9.0 (4.7-15.1)

9.9 (5.2-16.7)

   HPV31

5

3.7 (1.2-8.5)

4.1 (1.4-9.4)

   HPV45

5

3.7 (1.2-8.5)

4.1 (1.4-9.4)

   HPV58

5

3.7 (1.2-8.5)

4.1 (1.4-9.4)

   HPV33

4

3.0 (0.8-7.5)

3.3 (0.9-8.2)

   HPV35

2

1.5 (0.2-5.3)

1.7 (0.2-5.8)

   HPV51

2

1.5 (0.2-5.3)

1.7 (0.2-5.8)

   HPV52

2

1.5 (0.2-5.3)

1.7 (0.2-5.8)

   HPV42

1

0.7 (0.0-4.1)

0.8 (0.0-4.5)

   HPV56

1

0.7 (0.0-4.1)

0.8 (0.0-4.5)

   HPV70

1

0.7 (0.0-4.1)

0.8 (0.0-4.5)

Multiple types

6

4.5 (1.7-9.5)

5.0 (1.8-10.5)

   HPV 16&18

1

0.7 (0.0-4.1)

0.8 (0.0-4.5)

   HPV 45&51

1

0.7 (0.0-4.1)

0.8 (0.0-4.5)

   HPV 31&42

1

0.7 (0.0-4.1)

0.8 (0.0-4.5)

   HPV 31&52

1

0.7 (0.0-4.1)

0.8 (0.0-4.5)

   HPV 6&53&66

1

0.7 (0.0-4.1)

0.8 (0.0-4.5)

   HPV 53&56&58

1

0.7 (0.0-4.1)

0.8 (0.0-4.5)

HPVX (Unknown type)

4

3.0 (0.1-5.9)

3.3 (0.9-8.2)

Potential vaccine impact (***)

   

   HPV16, 18, 16&18

84

62.7 (53.9-70.9)

69.4 (60.4-77.5)

Total HPV positive cases

121

90.3 (84.0-94.7)

100.0

Total HPV analyzed cases

134

  
  1. (*) HPV prevalence (95% CI), among HPV analyzed cases (n = 134).
  2. (**) HPV type-specific relative contribution (95% CI), among HPV positive cases (n = 121).
  3. (***) Considering a 100% vaccine efficacy (without cross-protection).
  4. 95% CI: 95% Confidence Interval.