Table 1 Detection of HPV DNA in ICC specimens from Italy, by age at diagnosis and histopathological information
HPV analyzed cases (n) | HPV positive cases (n) | HPVprevalence % (95% CI) | |
|---|---|---|---|
Age (years) | |||
≤39 | 29 | 25 | 86.2 (68.7-96.1) |
40-49 | 36 | 35 | 97.2 (85.5-99.9) |
50-59 | 27 | 25 | 92.6 (75.7-99.1) |
≥60 | 42 | 36 | 85.7 (71.5-94.6) |
Histological type | |||
Squamous cell carcinoma | 112 | 101 | 90.2 (83.1-95.0) |
Adenocarcinoma | 17 | 16 | 94.1 (71.3-99.8) |
Adenosquamous cell carcinoma | 1 | 1 | 100.0 (25.0-100.0) |
Other | 4 | 3 | 75.0 (19.4-99.4) |
Degree of Necrosis | |||
<25% | 120 | 110 | 91.7 (85.2-95.9) |
25%-50% | 12 | 11 | 91.7 (61.5-99.8) |
51%-75% | 2 | 0 | 0.0 (0.0-84.2) |
Tumour Infiltration | |||
<10% | 1 | 1 | 100.0 (25.0-100.0) |
10%-25% | 7 | 6 | 85.7 (42.1-99.6) |
26%-50% | 43 | 38 | 88.4 (74.9-96.1) |
51%-75% | 41 | 39 | 95.1 (83.5-99.4) |
>75% | 42 | 37 | 88.1 (74.4-96.0) |
Mucosa | |||
Squamous mucosa | 15 | 14 | 93.3 (68.0-99.8) |
Endocervical mucosa | 10 | 9 | 90.0 (55.5-99.7) |
Squamous and endocervical mucosa | 20 | 18 | 90.0 (68.3-98.8) |
No mucosa | 89 | 80 | 89.9 (81.7-95.3) |
CIN III (*) | |||
Yes | 22 | 20 | 90.9 (70.8-98.9) |
No | 112 | 101 | 90.2 (83.1-95.0) |
AIS (**) | |||
Yes | 4 | 4 | 100.0 (39.8-100) |
No | 130 | 117 | 90.0 (83.5-94.6) |
Total | 134 | 121 | 90.3 (84.0-94.7) |