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Figure 2 | BMC Cancer

Figure 2

From: Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-κB

Figure 2

Dose dependent reduction in phosphorylated IκBα and total IκBα in S100A4-stimulated cells by Ser/Thr kinase inhibitors. II-11b cells were treated with 2 μM S100A4 and the inhibitors H-7 (A) and staurosporine (B) using the indicated concentrations. After one hour cells were harvested and analyzed by immunoblotting for expression of phosphorylated IκBα, total IκBα and α-tubulin as indicated. For total IκBα both short and long exposure times are shown.

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