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Table 5 Histological grade by age and family history.

From: Histological type and grade of breast cancer tumors by parity, age at birth, and time since birth: a register-based study in Norway

 

All women

(n = 9544)

Nulliparous

Women

Parous

Women

 

Total no.

Grade 3-4 (%)

Total no.

Grade 3-4 (%)

Total no.

Grade 3-4 (%)

Age at diagnosis

      

20-29

72

58.3**

25

68.0**

47

53.2*

30-39

818

54.8**

135

57.0**

683

54.3**

40-49

2793

43.2**

317

47.3**

2476

42.7**

50-59

3006

33.4(**)

371

34.5

2635

33.2(**)

60-69

2429

28.6(**)

343

28.3(**)

2086

28.6(**)

70-74

426

20.7(**)

70

18.6(**)

356

21.1(**)

P-valuea

 

<0.001

 

<0.001

 

<0.001

OR, unadjustedb

 

0.70**

 

0.65**

 

0.71**

Family history c

      

   No

3363

36.9

536

36.9

2827

36.9

   Yes

406

38.9

76

48.7

330

36.7

P-valuea

 

0.43

 

0.049

 

0.94

   < 50 yr

      

No

2221

40.8

307

45.0

1914

40.2

Yes

269

44.2

43

62.8

226

40.7

   P-valuea

 

0.28

 

0.028

 

0.88

   ≥ 50 yr

      

No

1142

29.2

229

26.2

913

30.0

Yes

137

28.5

33

30.3

104

27.9

   P-valuea

 

0.85

 

0.62

 

0.65

  1. Histological grade of breast cancer tumors by age at diagnosis and family history
  2. a Chi-square test for difference in proportions between groups, with significant cell-specific contributions to the chi-square statistic at 5% level marked with ** (Χ ≥ 1.96), and significant contributions at 10% level marked with * (Χ ≥ 1.64); in brackets if the observed number is lower than expected by chance
  3. b OR (grade 3-4 vs. grade 1-2) for linear trend through ordered categories of exposure variable, with significant test for trend (p < 0.05) marked with **
  4. c Mother/sister with a breast cancer diagnosis, restricted to 3769 cases with complete information
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BMC Cancer

ISSN: 1471-2407

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