Table 1 Effects of GF on the dynamic instability parameters of individual MTs

Rate (μm/min)

Growing

18.5 ± 4

12.0 ± 2.2 ^a

10.0 ± 2.0^a

Shortening

19.6 ± 5

12.7 ± 4.6 ^a

10.1 ± 2.6^a

Length Change (μm)

Growth length

2.0 ± 0.8

1.4 ± 0.6^b

1.0 ± 0.4^a

Shortening length

2.4 ± 0.7

1.4 ± 1^c

1.0 ± 0.3^a

% Time in phase

Growing

44.0 ± 10

33.0 ± 10^a

20.5 ± 6^a

Shortening

25.5 ± 10

14.5 ± 5^a

17.5 ± 4^b

Pause

30.5 ± 9

52.5 ± 9^a

62.0 ± 9^a

Frequency (events/min)

Catastrophe

4.0 ± 2

1.6 ± 0.5^a

2.3 ± 0.8^b

Rescue

10.0 ± 3

10.0 ± 4^d

10.0 ± 2.6^c

Frequency (events/μm)

Catastrophe

0.40 ± 0.2

0.5 ± 0.3^d

1.1 ± 0.5^a

Rescue

0.6 ± 0.3

0.9 ± 0.5^b

1.1 ± 0.3^a

Dynamicity (μm/min)

13.7 ± 4

5.7 ± 2^a

3.8 ± 1.2^a