Figure 5
From: The siRNA targeted to mdr1b and mdr1a mRNAs in vivosensitizes murine lymphosarcoma to chemotherapy
Silencing of mdr1b and mdr1a genes in lymphosarcoma RLS 40 by siRNAs. RT-PCR analysis (8% PAGE) of mdr1b mRNA level (A) and mdr1a mRNA level (B) 48 h after transfection of RLS40 ascites with 15 μg of luciferase or mdr1b/1a siRNA in vivo. (C) The expression levels of mdr1b and mdr1a genes in the tumor cells transfected with mdr1b/1a siRNA. The expression levels of mdr1b and mdr1a genes in the wild-type tumor cells and cells transfected with luc siRNA were used as controls.