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Table 2 Effect of WEB2170, DTIC and combined treatment on EAT growth.

From: Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy

Treatment ×106cells
Non treated 66.01 ± 16.07
DTIC 14.99 ± 6.16(*)
WEB2170 15.38 ± 4.26(*)
W + D 4.55 ± 2.16(*)
  1. 1 × 105 EAT cells were i.p. injected in BALB/c mice and after 10 days, the ascitis fluid was collected to determine tumour growth. WEB2170 (5 mg/Kg; i.p.) was given 30 min before inoculation of EAT cells and DTIC (40 μg/animal; i.p.) was given every 3 days after tumour implantation.
  2. (*) p < 0.05 compared with non treated group
  3. n = 5-9 animals/group