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Table 1 Effect of WEB2170 treatment on the percentage of apoptotic and necrotic cells during EAT growth.

From: Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy

Apoptotic cells % of total cells
  PBS WEB2170
  Day 7 Day 10 Day7 Day 10
  0.98 ± 0.98 1.38 ± 0.62 0.62 ± 0.26 1.72 ± 0.45
Necrotic cells 1.50 ± 0.35 0.30 ± 0.11(#) 0.60 ± 0.31(*) 0.70 ± 0.30
  1. 1 × 103 EAT cells were i.p. injected in BALB/C mice and the ascitis fluid was collected after 7 and 10 days to determine the percentage of apoptotic and necrotic cells. WEB2170 (5 mg/Kg; i.p.) was given 30 min before inoculation of EAT cells.
  2. (*) p < 0.05 comparing WEB2170-treated with PBS group
  3. (#) p < 0.05 comparing day 10 with day 7 within PBS or WEB2170 group
  4. n = 3-9 animals/group