Table 2 Affymetrix expression of growth factor receptor genes in MMC.
MFG | MGF receptor | probeset | Median (range) | P (%) |
|---|---|---|---|---|
| Â | Â | Â | on MMC | on MMC |
| Â | Â | Â | (n = 131) | (n = 131) |
   - IGF-1 | - IGF-1R | 203627_at | 19 (1-85) | 32 |
   - HGF | - c-Met | 203510_at | 78 (4-728) | 50 |
   - CCL3 | -CCR1 | 205098_at | 136 (26-2840) | 78 |
   - GDF15 | - not known | --- | --- | --- |
   - PTN | - RPTP-β/ζ/ | 204469_at | 24 (1-1958) | 48 |
   - BDNF | - NTRK2 | 207152_at | 84 (4-286) | 77 |
IL-6 family | Â | Â | Â | Â |
   - IL-6 | - IL-6R (gp80) | 205945_at | 502 (7-3657) | 99 |
| Â | - IL6ST (gp130) | 212195_at | 1681 (210-5680) | 100 |
   - CNTF | - CNTFR | NA | --- | --- |
   - OSM | - OSMR | 205729_at | 25 (1-88) | 58 |
   - LIF | - LIFR | 225575_at | 16 (1-203) | 15 |
   - IL-11 | - IL-11R | 204773_at | 61 (3-140) | 26 |
   - CLCF1 | - CRLF1 | 206315_at | 15 (2-91) | 0 |
other interleukins | Â | Â | Â | Â |
   - IL-1β | - IL-1R | 202948_at | 10 (1-63) | 1 |
   - IL-10 | - IL-10RA | 204912_at | 212 (24-912) | 92 |
| Â | - IL-10RB | 209575_at | 240 (98-536) | 100 |
   - IL-15 | - IL-15R | 207375_s_at | 142 (16-403) | 55 |
   - IL-21 | - IL-21R | 221658_s_at | 6 (1-395) | 5 |
TNF family | Â | Â | Â | Â |
   - TNF-α | - TNFRSF1A | 241944_x_at | 63 (4-233) | 66 |
   - BAFF | - TNFRSF13B/TACI | 207641_at | 266 (50-745) | 95 |
   - APRIL | - TNFRSF13C/Baff-R | NA | --- | --- |
| Â | - TNFRSF17/BCMA | 206641_at | 3794 (968-8301) | 100 |
EGF family | - ErbB1 | 211551_at | 56 (6-148) | 64 |
| Â | - ErbB2 | 216836_s_at | 30 (2-106) | 5 |
| Â | - ErbB3 | 202454_s_at | 47 (79-172) | 59 |
| Â | - ErbB4 | 214053_at | 51 (2-1091) | 38 |
VEGF family | -VEGFR1/FLT1 | NA | --- | --- |
| Â | -VEGFR2/FLK1 | NA | --- | --- |
| Â | -VEGFR3/FLT4 | NA | --- | --- |
FGF family | - FGFR1 | NA | --- | --- |
| Â | - FGFR2 | NA | --- | --- |
| Â | - FGFR3 | 204379_s_at | 4.2 (1-13160) | 10 |
| Â | - FGFR4 | NA | --- | --- |
Wnt family | - Frizzled1 (Frz1) | 204451_at | 75 (2-586) | 34 |
| Â | - Frz2 | 210220_at | 30 (1-680) | 30 |
| Â | - Frz3 | 219683_at | 80 (15-465) | 19 |
| Â | - Frz4 | 218665_at | 84 (2-348) | 92 |
| Â | - Frz5 | NA | --- | 8 |
| Â | - Frz6 | 203987_at | 229 (6-1425) | Â |
| Â | - Frz7 | 203706_s_at | 102 (12-2228) | 98 |
| Â | - Frz8 | 227405_s_at | 34 (3-338) | 93 |
| Â | - Frz9 | NA | --- | 15 |
| Â | - Frz10 | NA | --- | --- |
| Â | - LRP5 | NA | --- | --- |
| Â | - LRP6 | 225745_at | 70 (1-137) | 43 |
Jagged | - Notch1 | 218902_at | 85 (24-233) | 47 |
| Â | - Notch2 | 212377_s_at | 216 (43-1743) | 100 |
| Â | - Notch3 | 203238_s_at | 28 (1.4-95) | 2 |
| Â | - Notch4 | 205247_at | 40 (8-190) | 35 |