From: Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?
 |  | MLH1 methylation | BRAF | MLH1-93G>A | ||||
---|---|---|---|---|---|---|---|---|
Type | n | M | pM | Mut | G/G | G/A | A/A | NA |
Adenoma | 2 | 2 | 0 | 1 | 0 | 1 | 1 | 0 |
Carcinoma | 44 | 33 | 11 | 24 | 12 | 20 | 7 | 5 |
Age | Â | Â | Â | Â | Â | Â | Â | Â |
Total <50 | 13 | 9 | 4 | 4 | 4 | 7 | 2 | 0 |
Total ≥ 50 | 33 | 26 | 7 | 21 | 8 | 14 | 6 | 5 |
BRAF mut | 25 | 23 | 2 | 25 | 7 | 12 | 4 | 2 |