Figure 5
From: Cystatin E/M suppresses legumain activity and invasion of human melanoma
Over-expression of cystatin E/M suppressed melanoma cell invasion. A375 and MCC11 cells were transfected with pCST6 (closed bars) or empty vector (control; open bars) and migration through Matrigel coated transwell membranes was determined. The bars represent the average of four or three experiments for A375 and MCC11, respectively, with six replicate wells for each transfection group (A375, p < 0.01; MCC11, p < 0.05). Error bars represent the standard error of the mean (SEM).