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Table 2 Apoptotic and cell cycle data for cells derived from head and neck human oral carcinomas and from normal human oral mucosa.

From: Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistance

Cell type Treatment %CD44 high % Annexin positive cells in CD44 low % Annexin positive cells in CD44 high % cells in G2 in CD44 low % cells in G2 in CD44 high
HNSCC derived cells
(n = 11)
      
  Ctrl 24 h 3.9 ± 0.4 15.1 ± 11.5 8.9 ± 8.9 12.9 ± 1.2 23.0 ± 2.2##
  250 μM CP 24 h 6.8 ± 1.0* 38.5 ± 19.5 22.1 ± 16.7 15.0 ± 2.1 41.1 ± 9.7#
  20 ng/ml NCZ 24 h 6.0 ± 0.8 19.9 ± 10.3 3.5 ± 2.8 11.6 ± 1.9 31.4 ± 6.0#
  Ctrl 48 h 4.3 ± 0.7 14.9 ± 7.6 2.5 ± 1.6 14.1 ± 3.1 23.5 ± 5.3
  20 ng/ml NCZ48 h 11.0 ± 3.9** 36.3 ± 16.3 11.0 ± 4.8 17.1 ± 2.9 76.9 ± 23.2**
NOK
(n = 5)
      
  Ctrl 24 h 4.8 ± 1.7 5.2 ± 0.9 0.7 ± 0.4## 10.4 ± 1.9 20.9 ± 2.6#
  10mJ UV 24 h 7.5 ± 2.8 7.5 ± 2.8 1.3 ± 0.5# 28.9 ± 2.1* 44.9 ± 4.7##
  Ctrl 48 h 3.3 ± 0.6 15 ± 4.5 2.1 ± 0.3# 11.6 ± 1.8 16.0 ± 2.3
  250 μM CP 48 h 4.6 ± 0.9 28.8 ± 4.0 3.6 ± 0.5* ## 15.8 ± 4.0 28.6 ± 2.3
  1. Table key: Data are presented as mean ± SD of 3 independent assays. * p value < 0.05 when compared with the control group; ** p value < 0.01 when compared with the control group; # p value < 0.05 when compared with the CD44 low population from the same group; ## p value < 0.01 when compared with the CD44 low population from the same group.
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