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Table 1 Characteristics of the patients analyzed with RT-PCR and CK-ICC.

From: Clinical impact of different detection methods for disseminated tumor cells in bone marrow of patients undergoing surgical resection of colorectal liver metastases: a prospective follow-up study

  RT-PCR CK-ICC
  positive
N = 9
negative
N = 35
positive
N = 15
negative
N = 31
Male 5 (56) 26 (74) 12 (80) 20 (65)
Age (years), mean (se) 63.4 (3.7) 60.9 (1.3) 62.9 (2.3) 60.2 (1.6)
TNM stage of primary tumor     
1 1 (11) 3 (9) 2 (13) 1 (3)
2 1 (11) 6 (17) 2 (13) 4 (13)
3 3 (33) 9 (26) 5 (33) 8 (26)
4 4 (45) 17 (49) 6 (40) 18 (58)
Time span between PT and LM (months)     
< 12 6 (67) 20 (57) 8 (53) 23 (74)
> 12 3 (33) 15 (43) 7 (47) 8 (26)
Preoperative systemic chemotherapy     
No 4 (44) 25 (71) 12 (80) 18 (58)
Yes 5 (56) 10 (29) 3 (20) 13 (42)
Serum CEA level     
< 200 ug/l 5 (55) 30 (86) 13 (87) 25 (81)
> 200 ug/l 1 (11) 3 (9) 1 (7) 2 (7)
not assessed 3 (33) 2 (5) 1 (7) 4 (14)
No. of liver metastases     
1 3 (33) 14 (40) 5 (33) 12 (39)
> 1 6 (67) 21 (60) 10 (67) 19 (61)
Diameter of liver metastases (cm)     
< 5 7 (77) 28 (80) 12 (80) 26 (84)
> 5 2 (33) 7 (20) 3 (20) 5 (16)
MSKCC clinical risk score     
   0-2 (low) 4 (44) 24 (69) 12 (80) 20 (65)
   ≥ 3 (high) 5 (56) 11 (31) 3 (20) 11 (35)
Death 6 (67) 10 (29) 5 (33) 14 (45)
  1. Data presented in number (%), unless otherwise stated.
  2. *Abbreviations; PT, primary tumor; LM, liver metastases; CEA, carcino embryonic antigen; MSKCC, memorial sloan-kettering cancer center.