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Table 1 Characteristics of the patients analyzed with RT-PCR and CK-ICC.

From: Clinical impact of different detection methods for disseminated tumor cells in bone marrow of patients undergoing surgical resection of colorectal liver metastases: a prospective follow-up study

 

RT-PCR

CK-ICC

 

positive

N = 9

negative

N = 35

positive

N = 15

negative

N = 31

Male

5 (56)

26 (74)

12 (80)

20 (65)

Age (years), mean (se)

63.4 (3.7)

60.9 (1.3)

62.9 (2.3)

60.2 (1.6)

TNM stage of primary tumor

    

1

1 (11)

3 (9)

2 (13)

1 (3)

2

1 (11)

6 (17)

2 (13)

4 (13)

3

3 (33)

9 (26)

5 (33)

8 (26)

4

4 (45)

17 (49)

6 (40)

18 (58)

Time span between PT and LM (months)

    

< 12

6 (67)

20 (57)

8 (53)

23 (74)

> 12

3 (33)

15 (43)

7 (47)

8 (26)

Preoperative systemic chemotherapy

    

No

4 (44)

25 (71)

12 (80)

18 (58)

Yes

5 (56)

10 (29)

3 (20)

13 (42)

Serum CEA level

    

< 200 ug/l

5 (55)

30 (86)

13 (87)

25 (81)

> 200 ug/l

1 (11)

3 (9)

1 (7)

2 (7)

not assessed

3 (33)

2 (5)

1 (7)

4 (14)

No. of liver metastases

    

1

3 (33)

14 (40)

5 (33)

12 (39)

> 1

6 (67)

21 (60)

10 (67)

19 (61)

Diameter of liver metastases (cm)

    

< 5

7 (77)

28 (80)

12 (80)

26 (84)

> 5

2 (33)

7 (20)

3 (20)

5 (16)

MSKCC clinical risk score

    

   0-2 (low)

4 (44)

24 (69)

12 (80)

20 (65)

   ≥ 3 (high)

5 (56)

11 (31)

3 (20)

11 (35)

Death

6 (67)

10 (29)

5 (33)

14 (45)

  1. Data presented in number (%), unless otherwise stated.
  2. *Abbreviations; PT, primary tumor; LM, liver metastases; CEA, carcino embryonic antigen; MSKCC, memorial sloan-kettering cancer center.