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Table 2 Clones with recurrent copy number changes shared by cell lines and tissue specimens

From: Breast cancer cell lines carry cell line-specific genomic alterations that are distinct from aberrations in breast cancer tissues: Comparison of the CGH profiles between cancer cell lines and primary cancer tissues

A: Clones with recurrent copy number gains shared by cell lines and tissue specimens

Chromosomal region

Genes

Frequency

P-value

  

Cell lines

Tissue

 

1q44

FLJ10157

13/24

19/35

0.992806112

8q22.1

TSPYL5

15/24

22/35

0.977767962

8q21.3

NBS1, DECR1

14/24

20/35

0.927569885

8q23.1

MGC35555

14/24

20/35

0.927569885

1q21.1

-

12/24

18/35

0.914136773

1q21.2-1q21.3

PIP5K1A, PSMD4, KIAA1441

12/24

18/35

0.914136773

1q23.1

SH2D2A, INSRR, NTRK1

12/24

18/35

0.914136773

1q32.1

MDM4

12/24

18/35

0.914136773

1q42.11

CAPN2, TP53BP2

12/24

17/35

0.914136773

1q44

FLJ32001, CGI-49

12/24

17/35

0.914136773

1q44

OR1C1, OR9H1P, OR11L1

12/24

18/35

0.914136773

7p14.1

TRGJP2, TRGC1, TRGJ1

12/24

18/35

0.914136773

7p14.1

TRGJP1, TRGV11, TRGVB

12/24

17/35

0.914136773

8q24.22

-

12/24

17/35

0.914136773

17q25.3

TBCD

12/24

17/35

0.914136773

1q25.1

TNN, KIAA0040

14/24

21/35

0.898133861

8q21.3

NBS1

14/24

18/35

0.898133861

8q22.2

KCNS2, STK3

14/24

18/35

0.898133861

B; Clones with recurrent copy number losses shared by cell lines and tissue specimens

Chromosomal region

Genes

Frequency (%)

P-value

  

Cell lines

Tissue

 

17p11.2

DRG2, MYO15A, LLGL1, FLII

13/24

19/35

0.992806112

17p12

LOC388338, HS3ST3B1

15/24

22/35

0.977767962

11q23.2

ZBTB16

12/24

18/35

0.914136773

11q25

SPAS1

'12/24

18/35

0.914136773

17p13.3

NXN

'12/24

17/35

0.914136773

17p13.1

ASGR1, DLG4, ACADVL

14/24

21/35

0.898133861

17p13.1

MYH3, SCO1, MDS006

14/24

19/34

0.852726956