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Table 5 Correlations between serum concentrations of VEGF-165 and TIMP-1 and response to first-line treatment according to decrease of CA-125.

From: TIMP-1 and VEGF-165 serum concentration during first-line therapy of ovarian cancer patients

 

Response (% decrease of CA-125)

 

p-value

correlation coefficient r

TIMP-1 before surgery

0.375

0.174

TIMP-1 before CTX

0.150

0.265

TIMP-1 during CTX

0.480

0.127

TIMP-1 after CTX

0.554

0.107

VEGF before surgery

0.725

-0.07

VEGF before CTX

0.729

0.065

VEGF during CTX

0.414

-0.147

VEGF after CTX

0.671

-0.077

  1. P-values according to the Pearson correlation coefficients using continous serum values and relative decrease of CA-125.