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Table 3 Correlations between serum concentration of CA-125, TIMP-1 and VEGF and survival

From: TIMP-1 and VEGF-165 serum concentration during first-line therapy of ovarian cancer patients

 

PFS

 

OS

 
 

p-value

+/-

p-value

+/-

CA-125 before surgery

0.593

.

0.629

.

CA-125 before CTX

0.725

.

0.033*

-

CA-125 during CTX

0.627

.

0.308

.

CA-125 after CTX

<0.001

+

0.002*

+

TIMP-1 before surgery

0.534

.

0.195

.

TIMP-1 before CTX

0.499

.

0.980

.

TIMP-1 during CTX

0.781

.

0.380

.

TIMP-1 after CTX

0.152

.

0.007

+

VEGF before surgery

0.352

.

0.302

.

VEGF before CTX

0.043

+

0.230

.

VEGF during CTX

0.946

.

0.496

.

VEGF after CTX

0.006

+

0.023

+

  1. Correlations between serum concentration of CA-125, TIMP-1 and VEGF (below/above median) and survival. For progression-free survival (PFS) and overall survival (OS): p-values from the log-rank-test. +/- indicates the direction of a significant correlation. A positive correlation indicates a higher likelihood of an event (e.g. elevated CA-125 is associated with high likelihood of disease progression).
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BMC Cancer

ISSN: 1471-2407

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