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Table 1 Summary of parallel open, randomised clinical studies of moxibustion for cancer

From: Moxibustion for cancer care: a systematic review and meta-analysis

First author (year) Sample size
Condition
Intervention group (Regimen) Control group
(Regimen)
Main outcomes Intergroup differences Treated acupuncture points
Rationale for point selection
Cheng (2005) [18] 84
Nasopharyngeal carcinoma
(A) Moxibustion (once daily for 30 days, n = 42), plus radiotherapy and chemotherapy
Indirect
(B) Chemotherapy and radiotherapy, plus drug therapies for side effects (n = 42) Response rate NS, 1.05 [0.95, 1.16] CV8
n.r.
Chen (2000) [19] 56
Nasopharyngeal carcinoma
(A) Moxibustion (once daily for 30 days, n = 28), plus (B)
Indirect
(B) Chemotherapy and radiotherapy (n = 28), plus drug therapies for side effects 1) Response rate
2) Side effect of chemotherapy3) 5-year survival rate
1) NS, 1.10 [0.83, 1.44]
2) P < 0.05 in favour of A
3) NS, 1.40 [0.75, 2.60]
CV8
n.r.
Cao (1997) [20] 36
Gastric cancer
(A) Moxibustion (3 times weekly, n.r, n = 12), plus (B)
Indirect
(B) Chemotherapy(n = 12)
(C) Chemotherapy plus drug therapies for side effects (n = 12)
1) Response rate
2) Side effect of chemotherapy
1) NS, 2.0 [0.82, 2.34]
2) P < 0.05 in favour of A
CV8
n.r.
Liu (2001) [21] 81
Various cancer
(Malignant tumor)
(A) Moxibustion (once daily, n.r, n = 30), plus (B)
Indirect
(B) Chemotherapy (n = 35), plus herbal medicine (Gubenyiliu III 400 ml, twice a day)
(C) Chemotherapy (n = 16)
1) Response rate
2) Living quality
1) NS, 0.99 [0.87, 1.12]
2) NS, 0.22 [-0.27, 0.71]
GV14, BL17, ST36
n.r.
Bian (2004) [22] 44
Various cancer (cancer pain)
(A) Moxibustion (2-3 times daily for 20 days, n = 23), plus morphine injection (acupoint, 5-10 mg, twice a day)
Indirect
(B) Morphine injection (10-20 mg, 2-3 times a day, n = 21) Living quality P < 0.00001, 2.03 [1.29, 2.78] in favour of A GV14, CV4, ST36, LI4, ashi-point
n.r.
  1. NS: not significant; n.r.: not reported