HMG-CoAR Autoscore is Associated with an Improved RFS. There was an excellent correlation between automated and manual cytoplasmic intensity (A). A HMG-CoAR autoscore was calculated by combining cytoplasmic intensity and the percentage of positive tumour cells. The distribution of the HMG-CoAR autoscore is illustrated in the histogram (B). Using a threshold of the 25th percentile, an increased HMG-CoAR autoscore was associated with a prolonged RFS (C) but not OS (D).