Differential profiling of breast cancer plasma proteome by isotope-coded affinity tagging method reveals biotinidase as a breast cancer biomarker

Table 2 List of proteins and their abundance ratios between cancer and control

Uniprot*	Gene name	Abundance ratio (cancer/control)
		ICAT (N = 2)^†	Western blot (N = 2)^†	Western blot (n = 12)^‡	Western blot (n = 42)^‡
O00533	CHL1	2.05	0.66
P19652	ORM2	1.85	2.05	1.01
P08571	CD14	1.69	1.29	1.78
P43251	BTD	0.44	0.51	0.43	0.52
P22352	GPX3	0.37	0.53	0.42	1

*Uniprot, protein accession number in the SWISS-PROT/TrEMBL database.
^† N denotes pooled plasma samples of breast cancer (n = 6) and normal healthy control (n = 6)
^‡ n, the number of individual samples.

ISSN: 1471-2407