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Table 1 Cell cycle and DNA damage repair genes with altered expression following CRY2 silencing.

From: Phenotypic effects of the circadian gene Cryptochrome 2 on cancer-related pathways

Gene RefSeq Description Array Fold Change Q-Value qPCR Fold Change
BCCIP NM_078469 BRCA2 and CDKN1A interacting protein 2.33 0.0021 1.57
BCL2 NM_000633 B-cell CLL/lymphoma 2 -1.47 0.0487 -1.50
CCND1 NM_053056 Cyclin D1 1.51 0.0087 1.33
CDKN1A NM_000389 Cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.71 0.0001 1.98
GADD45A NM_001924 Growth arrest and DNA-damage-inducible, alpha 1.92 0.0015 2.16
HERC5 NM_016323 Hect domain and RLD 5 3.93 0.0000 2.28
MCM5 NM_006739 Minichromosome maintenance complex component 5 -1.58 0.0415 -1.46
PPP1R15A NM_014330 Protein phosphatase 1, regulatory (inhibitor) subunit 15A 2.55 0.0004 2.45
SUMO1 NM_001005781 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 2.00 0.0002 1.32
UBA1 NM_003334 Ubiquitin-like modifier activating enzyme 1 1.58 0.0232 1.43