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Table 1 Cell cycle and DNA damage repair genes with altered expression following CRY2 silencing.

From: Phenotypic effects of the circadian gene Cryptochrome 2 on cancer-related pathways

Gene

RefSeq

Description

Array Fold Change

Q-Value

qPCR Fold Change

BCCIP

NM_078469

BRCA2 and CDKN1A interacting protein

2.33

0.0021

1.57

BCL2

NM_000633

B-cell CLL/lymphoma 2

-1.47

0.0487

-1.50

CCND1

NM_053056

Cyclin D1

1.51

0.0087

1.33

CDKN1A

NM_000389

Cyclin-dependent kinase inhibitor 1A (p21, Cip1)

1.71

0.0001

1.98

GADD45A

NM_001924

Growth arrest and DNA-damage-inducible, alpha

1.92

0.0015

2.16

HERC5

NM_016323

Hect domain and RLD 5

3.93

0.0000

2.28

MCM5

NM_006739

Minichromosome maintenance complex component 5

-1.58

0.0415

-1.46

PPP1R15A

NM_014330

Protein phosphatase 1, regulatory (inhibitor) subunit 15A

2.55

0.0004

2.45

SUMO1

NM_001005781

SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)

2.00

0.0002

1.32

UBA1

NM_003334

Ubiquitin-like modifier activating enzyme 1

1.58

0.0232

1.43