Figure 6
From: XIAP is not required for human tumor cell survival in the absence of an exogenous death signal
Effect of XIAP depletion on chemosensitivity of HCT-116 and SW620 cells. Cells were electroporated with 1 μM control siRNA (con siRNA) or 1 μM s1455 XIAP siRNA. HCT-116 and SW-620 were treated with an array of chemotherapeutic agents for 24 hr (A and C, respectively) or 48 hr (B and D). For the 24 hr exposure, the agents were added 32 hr following electroporation. For the 48 hr exposure, the agents were added 24 hr following electroporation. Untreated cells (black circle); Electroporated cells (black square); 1 μM control siRNA (black triangle) XIAP siRNA (inverted black triangle).