Reduced task-related activation in individual subjects during encoding, recognition and rotation at time
. Task specific ROIs were defined by significant activation (over crosshair viewing) during the individual tasks in a mixed-effects GLM and the average Z-scores within these regions were determined for each subject (and for each task) at time1 and time2. For each subject, the difference in average z-scores was calculated (time2 - time1) and thus negative scores represent a decrease in task-related activation within an individual. Each point represents time2 - time1 from a single subject. See Table 2 for statistical details.