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Table 4 Risk of breast cancer in relation to serum concentrations of organochlorines in quartiles by estrogen receptor status.

From: Organochlorine exposures influence on breast cancer risk and survival according to estrogen receptor status: a Danish cohort-nested case-control study

Organochlorines Estrogen receptor positive Estrogen receptor negative
in quartiles (ng/mL) Cases/controls Adjusted RR (95% CI)a p trendb Cases/controls Adjusted OR (95% CI) p trend
HCB
I <206.50 36/56 1.0 ref.c   19/23 1.0  
II 206.50-269.75 20/55 1.1 (0.6-1.8)   8/23 0.5 (0.2-1.4)  
III 269.75-335.75 22/56 1.0 (0.6-1.7)   11/23 0.8 (0.3-2.2)  
IV >335.75 36/55 1.2 (0.7-2.1) >0.20 6/23 0.4 (0.1-1.4) >0.20
Dieldrin
I <12.01 27/57 1.0   6/23 1.0  
II 12.01-28.30 28/56 1.3 (0.7-2,2)   5/23 1.2 (0.3-5.4)  
III 28.30-57.11 33/57 1.5 (0.8-2.7)   13/23 4.9 (0.9-28.3)  
IV >57.11 28/56 1.4 (0.8-2.5) >0.20 20/23 7.6 (1.3-46.1) 0.01
ΣPCB
I <811.11 36/57 1.0   14/23 1.0  
II 811.11-1076.04 24/56 1.1 (0.6-1.7)   11/23 1.0 (0.4-2.7)  
III 1076.04-1405.73 20/57 0.7 (0.4-1.2)   11/23 1.3 (0.4-3.9)  
IV >1405.73 36/56 1.3 (0.8-2.2) >0.20 8/23 0.8 (0.3-2.6) >0.20
p,p'-DDE
I <741.04 33/57 1.0   14/23 1.0  
II 741.04-1129.75 29/56 0.7 (0.4-1.2)   11/23 0.9 (0.3-2.5)  
III 1129.75-1688.85 25/57 0.8 (0.5-1.3)   10/23 0.7 (0.2-2.0)  
IV >1688.85 29/56 0.9 (0.6-1.5) >0.20 9/23 0.6 (0.2-1.7) >0.20
  1. a Odds ratio, 95% confidence interval, adjusted for age, weight, parity, and hormone replacement therapy; b two sided p-value for linear trend in OR's; c reference category. Cases with missing information on confounders were excluded.