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Table 3 Subgroup meta-analysis: role of PCI on time to relapse in the brain assessing brain metastases incidence (10 studies evaluable)

From: Prophylactic cranial irradiation in small cell lung cancer: a systematic review of the literature with meta-analysis

 

n studies

HR

Initial PCI

5

0.29 (0.12 - 0.71)

Limited disease

3

0.43 (0.28 - 0.64)

All stages diseases

7

0.50 (0.39 - 0.65)

Brain CT scan for staging

4

0.52 (0.40 - 0.68)

Brain CT scan before randomisation

2

0.44 (0.32 - 0.62)

No CT scan before randomisation

2

0.51 (0.38 - 0.63)