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Table 1 Trials characteristics

From: Prophylactic cranial irradiation in small cell lung cancer: a systematic review of the literature with meta-analysis

Authors

Dates

Stage

Cerebral

PCI (Gray)

Timing of PCI

N patients

   

work-up

 

administration

 

Jackson [18]

1977

1

2

30

1

29

Beiler [24]

1979

1

2

24

1

54

Hansen [22]

1980

2

2

40

3

109

Maurer [26]

1980

1

2

30

1

153

Eagan [20]

1981

2

1

36

3

30

Aisner [27]

1982

1

1

30

2

29

Seydel [21]

1985

2

2

30

1

217

Niiranen [25]

1989

2

2

40

1

51

Ohonoshi [23]

1993

1

1

40

2

46

Arriagada [16]

1995

1

1

24

2

294

Gregor [19]

1997

2

3

8 - 40

2

314

Laplanche [17]

1998

1

1

24

2

211

  1. Stage: 1: all 2: limited disease Cerebral work-up: 1: brain CT scan 2: brain scintigraphy 3: clinical Timing: 1: at initiation of chemotherapy 2: CR consolidation 3: consolidation only
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